The partial thromboplastin time: defining an era in coagulation

Laboratory Methodologic Approach in Prolonged Activated Partial Thromboplastin Time Test

The pathological activated partial thromboplastin time test is a data that we can find in all clinical laboratories routinely. The hemato-coagulative clinical case here reported aims to point out how the laboratory can provide a correct diagnosis by methodological rational setting and, consequently, carry out an appropriate therapy, or reassure the patient that the pathological data will not ca...

The partial thromboplastin (cephalin) time test.

Nine partial thromboplastin (cephalin) reagents have been compared in a parallel investigation of groups of patients on ;long-term' anticoagulants, a group with moderate haemophilia, and patients on heparin infusion. Results with the seven commercial reagents and a human cephalin extract have been correlated with those of a specially prepared and standardized reference preparation of human brai...

Fluorescence-based blood coagulation assay device for measuring activated partial thromboplastin time.

The measurement of blood clotting time is important in a range of clinical applications such as assessing coagulation disorders and controlling the effect of various anticoagulant drug therapies. Clotting time tests essentially measure the onset of clot formation which results from the formation of fibrin fibers in the blood sample. However, such assays are inherently imprecise due to the highl...

Evaluation of Antiphospholipid Antibodies and Activated Partial Thromboplastin Time in Women with Adverse Outcome of Pregnancy

Adverse outcome of pregnancy is a potentially dangerous complication of conception and affects 15-20% of pregnancies. According to recent studies increased level of blood antiphospholipids antibodies, if accompanied by predisposing factors, can be an adverse event in human pregnancy. The aim of the present study was to compare the maternal serum levels of anticardiolipin and antiphosphatidyl se...

A further face of the partial thromboplastin time APTT.